Fibrates but not statins increase plasma selenium in dyslipidemic aged patients – The EVA study

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Fibrates but not statins increase plasma selenium in dyslipidemic aged patients--the EVA study.

This secondary analysis of "Etude du Vieillissement Artériel" (EVA) study reports the effect of fibrates and statins on plasma selenium concentration and its 9-year change in free-living dyslipidemic elderly. Dyslipidemic patients were categorized in three sub-groups according to final low-density lipoprotein (LDL)-cholesterol level or hypolipidemic treatment: non-treated dyslipidemic (LDL-chol...

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Statins but not fibrates improve the atherogenic to anti-atherogenic lipoprotein particle ratio: a randomized crossover study

BACKGROUND Prior studies suggested low density lipoprotein particle (LDLP) size is a predictor of atherosclerosis. Knowledge of effects of lipid lowering drugs on lipoprotein subclasses is useful. We treated subjects with hyperlipidemia sequentially with statins and fibrates, the 2 main classes of lipid lowering therapy and studied changes in NMR lipoprotein subclasses. METHODS 35 subjects (2...

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Factors associated with longitudinal plasma selenium decline in the elderly: the EVA study.

Selenium status decreases in elderly populations. Cardiovascular diseases are the primary cause of death in the French elderly, and selenium may protect against cardiovascular diseases. The present work aims to evaluate the relationships between cardiovascular-related risk factors and plasma selenium variability in an elderly population during a 9-year period. Seven hundred fifty-one subjects f...

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ژورنال

عنوان ژورنال: Journal of Trace Elements in Medicine and Biology

سال: 2009

ISSN: 0946-672X

DOI: 10.1016/j.jtemb.2008.08.001